THF SEC Mark-Houwink-Sakurada Correction

Content Developed by Dr Dominik Konkolewicz

The first spreadsheet and the associated read-me file can be used to correct size exclusion chromatography (SEC) derived number average molecular weights (Mn), weight averaged molecular weight (Mw) and molar mass dispersity (Mw/Mn). Select the tab based on either poly(styrene) (PSty) or poly(methyl methacrylate) (PMMA) standards for the tetrahydrofuran (THF) eluent. Note this correction only applies to PMMA or PSty based apparent molecular weights for the listed polymers where THF is the solvent.

The second spreadsheet and the read-me file can correct the molecular weight distribution (full trace) from PMMA or PSty standards to the molecular weight distribution of the analyzed polymer, so long as the MHS corrections are known.

Molecular Weight Distribution Apparent and Corrected

All that is needed to use these Mark-Houwink-Sakurada correction spreadsheets is Microsoft Excel.

Original Parameters Derived from Gruendling, T., Junkers, T., Guilhaus, M. and Barner-Kowollik, C. (2010), Mark–Houwink Parameters for the Universal Calibration of Acrylate, Methacrylate and Vinyl Acetate Polymers Determined by Online Size-Exclusion Chromatography—Mass Spectrometry. Macromol. Chem. Phys., 211: 520-528. https://doi.org/10.1002/macp.200900323, Eda G., Liu J., Shivkumar S. (2007) “Solvent effects on jet evolution during electrospinning of semi-dilute polystyrene solutions” Eur. Polym. J., 43, 1154-1167, https://doi.org/10.1016/j.eurpolymj.2007.01.003 and Hutchinson R. A., Beuermann S., Paquet Jr D. A., McMinn J. H. , Jackson C., (2010) “Determination of Free-Radical propagation Rate Coefficients for Cycloalkyl and Functional Methacrylates by Pulsed-Laser Polymerization” Macromolecules 31, 1542-1547, https://doi.org/10.1021/ma971307u.

If using this set of Mark-Houwink spreadsheet in your research resulting in publication, MACRO asks that you acknowledge the spreadsheet as follows. “We acknowledge the Mark-Houwink-Sakurada Correction developed by The Konkolewicz Group provided by the Macromolecular Alliance for Community Resources and Outreach.” It is also critical to cite the references that contain the Mark-Houwink-Sakaruda Parameters.